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T3088 |
N-Ethylmaleimide
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1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM |
Cysteine Protease
,
DUB
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N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies. |
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T15735 |
Leptomycin B
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CI 940,LMB |
CRM1
,
Antibiotic
,
Antifungal
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Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ... |
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T17731L |
CL2A-SN-38 DCA 1279680-68-0(free base)
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Others
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CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibito... |
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TP1358 |
Peptide M
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Peptide M is a synthetic Peptide, 50 aa, derived from streptococcus M protein, containing an additional c-terminal cysteine residue. |
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T17732 |
CL2A
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Others
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|
CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuz... |
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T82394 |
FLAG-Cys
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FLAG-Cys is a Flag peptide modified by the addition of a cysteine (Cys) residue, known to exhibit immunogenicity [1]. |
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T76545 |
Cys(Npys)-TAT (47-57)
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Cys(Npys)-TAT (47-57), a peptide fragment corresponding to the transduction domain of the TAT peptide, features an activated cysteine residue C and is capable of electrostatically interacting with plasmid DNA. Notably, T... |
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T83750 |
Melittin (C-Term Cysteine labeled) TFA
|
Mel-Cys |
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Melittin (C-term cysteine labeled), a variant of the toxic bee venom peptide melittin featuring a cysteine residue at its C-terminus, effectively induces hemolysis in isolated human red blood cells at both endosomal and ... |
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T78634 |
2′-Thioadenosine
|
PD157432 |
EGFR
|
|
2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against ErbB-2. It achieves covalent inactivation of ErbB-1 through... |
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T78949 |
AM841
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|
Cannabinoid Receptor
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AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor. It diminishes forskolin-stimulated cAMP accumulation and slows gastroi... |
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T80362 |
Human α-Defensin 6
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Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion. It achieves this through the formation of ordered self-assembly fibrils and nanonets, wh... |
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T4413 |
Poseltinib
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Poseltinib is an orally active, selective, and irreversible Bruton's tyrosine kinase (BTK) inhibitor, exhibiting a half-maximal inhibitory concentration (IC 50) of 1.95 nM. It demonstrates 0.3, 2.3, and 2.4-fold greater ... |
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T17731 |
CL2A-SN-38
|
|
Others
|
|
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific ant... |
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T63351 |
MS8511
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|
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MS8511, a selective covalent irreversible inhibitor of G9a/GLP, targets a cysteine residue at the substrate binding site, displaying IC50 values of 100 nM (G9a) and 140 nM (GLP), alongside Kd values of 44 nM (G9a) and 46... |
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T70128 |
Olmutinib hydrochloride
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|
|
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Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor, used in the treatment of T790M mutation positive non-small cell lung cancer. Olmutinib covalently... |
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T80249 |
Epsilon-V1-2, Cys-conjugated
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|
PKC
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Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur... |
